PRDX6 and neoplasm: Mean tumor area/total area was reduced in the PRDX6 knockout group compared to the wild-type group [46.169 ± 17.873 in wild-type rats (n = 8) vs. 10.651 ± 8.223 in PRDX6 knockout rats (n = 8)] (P < 0.001) (Fig. 3E).