Currently, intensive challenges have been conducting in combination with antibody, chemical composites and photothermal synergistic effects to enhance anti-tumor activity.43, 44, 45, 46, 47, 48 Therein, photothermal therapy with black phosphorus (BP) based combinations, such as BP-CD47 antibody, BP-quantum dots loaded siRNA, and BP-integrated cellulose has especially much attention due to its optical properties, higher surfaces, and biocompatibilities. Here, CD47 is linked to neoplasm.