Previous studies12, 13, 14, 15, 16 have found that N‐terminal pro B‐type natriuretic peptide (NT‐proBNP), d‐dimer, and the cardiac structural index left atrial diameter (LAD) are strongly associated with the development of AF and could help refine the risk assessment of IS related to NVAF. Here, NPPB is linked to atrial fibrillation.