This study examined the effect of SNHG3 on several tumor phenotypes, and a series of in vitro functional experiments showed that SNHG3 overexpression could promote the proliferation, migration, invasion, and angiogenesis of BLCa cells, indicating SNHG3 was positively correlated with the malignant transformation of BLCa. Here, SNHG3 is linked to bladder transitional cell carcinoma.