The result of our study that serum CXCL10 concentrations of patients with late-stage (AJCC stages IIB, III, and IV) CESC were higher than those with early-stage CESC suggested CXCL10 might take part in the progression of CESC and be a prognostic marker of the CESC patients. The gene discussed is CXCL10; the disease is cervical squamous cell carcinoma.