The possible causes of vision loss were the progression of a pre-existing cataract (n=6), transient hypotony (n=1), an astigmatism more than 3 diopters (n=1), diabetic retinopathy progression (n=2), possible glaucoma progression (n=2), pre-existing macular oedema resulting from central retinal vein occlusion progression under retinal photocoagulation and anti-VEGF treatment (n=1). The gene discussed is VEGFA; the disease is macular retinal edema.