It is possible that this apparent discrepancy is due to a lack of tissue specificity of the regulatory region containing the variant rs72904286, which could form non-tissue specific contacts with TFAP2B. Indeed, we demonstrate a similar number of chromatin interactions among glaucoma associated eQTLs and risk variants in both retina and in neurons, demonstrating weak tissue specificity for this eye disease. This evidence concerns the gene TFAP2B and eye disorder.