ARMS2 and age-related macular degeneration: We also identified 5 AMD lead variants overlapping with a CRE and localizing to gene bodies (ARHGAP21, ARMS2/HTRA1, CNN2, APOE and TNFRSF10A genes) and one AMD lead variant (rs3750846) overlapping with a SE and gene bodies of ARMS2 and BX842242.1 (Supplementary Data 4).