ZNF148 and breast carcinoma: To determine the clinical relevance of the observed cell line data, we examined the relapse-free survival (RFS) of breast cancer patients based on the expression level of ZNF148. In all breast cancer subtypes, patients with a higher level of ZNF148 had a better survival chance, consistent with the observed tumor suppressive and anti-migratory effect of ZNF148 (Fig. 3F).