DNAJC5 and malaria: Interestingly, a newer version of the recombinant malaria vaccine RTS,S known as R21, which displays the circumsporozoite protein (CSP) antigen at full valency in a highly dense array on the hepatitis B surface antigen scaffold, elicited enhanced antigen-specific antibody titers and reduced anti-scaffold responses compared with RTS,S,86 and is a more efficacious vaccine.87