PVs in other genes, including BARD1 (MIM: 601593), RAD51C (MIM: 602774), RAD51D (MIM: 602954), TP53 (MIM: 191170), PTEN (MIM: 601728), and NF1 (MIM: 613113), are also associated with breast cancer risk, but to a lesser extent, and account for a small proportion of the familial aggregation.2 This evidence concerns the gene RAD51C and breast carcinoma.