Following infection, the NDUFA4−/− iPSC lines overexpressing NDUFA4 showed a higher percentage of ZIKV-E+ cells (ZIKVPR: Figures 2N and 2O; ZIKVU: Figures S2M and S2N) and higher level of ZIKV (+) and (−) vRNA strands (ZIKVPR: Figure 2P; ZIKVU: Figure S2O) at 72 hpi compared to NDUFA4−/− iPSC lines. This evidence concerns the gene COXFA4 and infection.