IL24 and neoplasm: Furthermore, combination of IL24 and Oncostatin M(OSM) increased antitumor activity in comparison to isolated treatment inmelanoma (Xu et al., 2014) and livercancer, combining two different oncolytic adenoviruses expressing IL-24 or SOC3Sresulted in higher tumor suppression when compared to alone treatments or withan empty oncolytic adenovirus (Cao et al.,2011a).