Encouragingly, we also found this TUBB3+CD68 TAM subset in a 10× scRNA-seq dataset of human non–small cell lung cancer (NSCLC) biopsy with strong expression of neuronal genes including BMP7, SHANK, CHL1, and PAX6 (Fig. 2A). The gene discussed is SHANK2; the disease is non-small cell lung carcinoma.