The Kaplan-Meier survival analysis on TCGA database that includes 320 primary GBM patients suggests that high NRP1 expression (median cutoff) is of slight worsen prognosis (log-rank p-value 0.0204, Wilcoxon p-value 0.0072), with a noticeable difference in the earlier time points (Figure 2E). The gene discussed is NRP1; the disease is glioblastoma.