TRPV1 and asthma: Taking into account their functions, it well appears how a prolonged and intense stimulation of TRPV1 and TRPV4 plays a crucial role in the pathogenesis of some airway diseases, such as chronic cough and asthma, as well as viral-mediated airway damage, since TRPV1 and TRPV4 are both involved into host–pathogen contacts including the binding, entry and replication of the viruses (81, 82).