VHL and osteomyelitis: Using LysMCre and the corresponding floxed Hif1afl/fl and Vhlfl/fl alleles, myeloid-lineage conditional knockouts of Hif1a (Hif1afl/fl, LysMCre+/-; Hif1aΔMyeloid) and Vhl (Vhlfl/fl, LysMCre+/-; VhlΔMyeloid) were generated and subjected to S. aureus osteomyelitis.