Emerging publications have reported that TPX2 overexpression is closely related to the development of various malignant tumors, including cervical cancer, esophageal squamous cell carcinoma and pancreatic cancer (Chang et al., 2012; Hsu et al., 2014; Gomes-Filho et al., 2020). The gene discussed is TPX2; the disease is familial pancreatic carcinoma.