Seven variants in IL-6 (rs140764737, rs142164099, rs2069849, rs142759801, rs190436077, rs148171375, rs13306435) and five variants in IL-6R (rs2228144, rs2229237, rs2228145, rs28730735, rs143810642) appeared to alter the binding of IL-6 and IL-6R, which can be implicated in the pathogenetic mechanisms associated with COVID-19 severity and its complications (Strafella et al., 2020). The gene discussed is IL6; the disease is COVID-19.