ALPL mRNA (7.2 fold, p = 0.037) and RUNX2 mRNA (2.8 fold, p = 0.044) was up-regulated in OM at day 7, while in CaP-calcified SMCs, we observed a 1.3 fold increase of RUNX2 mRNA (p = 0.010) and no change in ALPL mRNA at day 3 (Figures 1E–H). Here, RUNX2 is linked to ocular melanoma.