MRAS and coronary artery disorder: In addition to the genome-wide significant SNP in JCAD, RNAm-SNPs in other important CAD susceptibility genes were also identified, including MRAS and TCF21. These RNAm-SNPs are not genome-wide significant, but they significantly affected the expression levels of MRAS and TCF21, and the expression levels of MRAS and TCF21 were genetically associated with CAD.