The Abeta deposition areas in the hippocampus in different groups were as follows: AD+NS vs. AD+Dex, 1.00 ± 0.24 vs. 0.45 ± 0.14 AU, p < 0.001; AD+Dex vs. AD+Dex+Y, 0.45 ± 0.14 vs. 0.89 ± 0.11, p < 0.001. Here, APP is linked to Alzheimer disease.