The Abeta deposition areas in the hippocampus DG in different groups were as follows: AD+NS vs. AD+Dex, 1.00 ± 0.32 vs. 0.37 ± 0.14 AU, p < 0.001; AD+Dex vs. AD+Dex+Y, 0.37 ± 0.14 vs. 0.90 ± 0.23, p = 0.001. The gene discussed is APP; the disease is Alzheimer disease.