These results revealed that the cancer subtype with the highest LRP1B mutation rate was prostate cancer (5/14, 35.7%), followed by small-cell lung cancer (7/24, 29.2%), gastric cancer (34/126, 27.0%), and cervical cancer (4/15, 26.7%); the average mutation rate was observed to be 15.2% (255/1683) (Figure 2G and Supplementary Table S5). Here, LRP1B is linked to Familial prostate cancer.