Additionally, MFAP2 expression was correlated with immunoinhibitory in gliomas, such as ADORA2A, CD96, CD244, CSF1R, HAVCR2, IDO1, IL10, IL10RB, KDR, LAG3, LGALS9, PDCD1, PDCD1LG2, PVRL2, TGFB1, and TGFBR1, which were positively correlated with MFAP2 expression in both LGG and GBM (Figure 6). This evidence concerns the gene PDCD1 and central nervous system cancer.