We found that the necroptosis-related genes MYC, DNMT1, BACH2, LEF1, and BNIP3 and the ferroptosis-related genes BNIP3, RPL8, HSPB1, ELAVL1, HIC1, SCP2, SLC38A1, MYB, MTDH, and LONP1 were overexpressed in normal samples compared with CAD samples. Here, RPL8 is linked to coronary artery disorder.