We found that the necroptosis-related genes MYC, DNMT1, BACH2, LEF1, and BNIP3 and the ferroptosis-related genes BNIP3, RPL8, HSPB1, ELAVL1, HIC1, SCP2, SLC38A1, MYB, MTDH, and LONP1 were overexpressed in normal samples compared with CAD samples. This evidence concerns the gene LEF1 and coronary artery disorder.