By contrast, the necroptosis-related genes FADD, ITPK1, TNFSF10, STAT3, and DNMT1 and the ferroptosis-related genes NCF2, CBS, FTL, MAP3K5, MAPK14, STAT3, PGD, SLC38A1, MYB, MTDH, and LONP1 displayed decreased expression in normal samples compared with those in CAD samples. The gene discussed is MAP3K5; the disease is coronary artery disorder.