Given the rule of “Jun-Chen-Zuo-Shi” in TCM formula theories (Wang et al., 2020a) and the analysis of network pharmacology, SR was responsible for 35% of the weight and 36.7% of the targets in the CW formula and was, thus, considered the major ingredient “Jun,” the targets of which were enriched in infections, cancers, the IL-17 signaling pathway, and neurotransmitter receptor activity, as well as liver diseases including hepatitis and non-alcoholic fatty liver disease. This evidence concerns the gene IL17A and metabolic dysfunction-associated steatotic liver disease.