APOA1 and neoplasm: Multivariate Cox analysis identified ApoA-I levels (HR: 0.717, 95% confidence interval [95% CI]: 0.527–0.976, P = 0.034), the number of liver metastases (HR: 1.760, 95% CI: 1.215-2.599, P = 0.004), type of liver metastases (HR: 0.598, 95% CI: 0.409-0.862, P = 0.007), tumor location (HR: 1.530, 95% CI: 1.086–2.128, P = 0.013), cN classification (HR: 1.422, 95% CI: 1.047–1.927, P = 0.024), primary surgery (HR: 0.659, 95% CI: 0.466-0.935, P = 0.019), and chemotherapy (HR: 0.628, 95% CI: 0.452-0.880, P = 0.006) as being significant independent predictors of survival in patients with CRLM.