Using a generalized model, logistic regression analysis was performed on the above items with statistically significant differences and assigned values, family history of colorectal cancer (no = 0, yes = 1), alcohol consumption (no = 0, yes = 1), frequent consumption of pickled food and grilled food (no = 0, yes = 1), MMP-2-735 (C/T) genotype (CT or TT type = 0, CC type = 1), MMP-9-1562 (C/T) genotype (CC or CT type = 0, TT type = 1). The gene discussed is MMP2; the disease is colorectal cancer.