Furthermore, bolus insulin dose was higher (0.40 vs 0.34 U/kgd, P = 0.035), FCP was higher in patients with MetS (48.6 vs 25.2 pmol/L, P = 0.017), and HbA1c was much higher in the MetS group (9.1% vs 7.9%, P = 0.004). The gene discussed is INS; the disease is metabolic syndrome.