Consistent with the two datasets, MVP, GRN, and ERP29 expression were significantly upregulated, and RNF128, NFYB, and KPNA3 were significantly downregulated in the dysferlinopathy patients compared with the controls (Figure 5C). The gene discussed is NFYB; the disease is neuromuscular disease caused by qualitative or quantitative defects of dysferlin.