human ADPKD kidney tissue; Ksp/Cre; Pkd1F/F mouse, Ksp/cre;Kif3aF/F mouse, Pkhd1/cre;Pkd2F/F mouse, Pkhd1−/− mouse, Pkhd1/cre;Hnf-1βF/F mouse. Here, PKHD1 is linked to autosomal dominant polycystic kidney disease.