PTBP2 and familial pancreatic carcinoma: PTBP1 was frequently altered in colorectal cancer, pancreatic cancer, and ovarian cancer; PTBP2 was frequently altered in non-small cell lung cancer, lung cancer, and ovarian cancer; and PTBP3 was frequently altered in pancreatic cancer, soft tissue sarcoma, and colorectal cancer (Figures 2B–D).