Considering individual groups, regardless of ZnT3 genotype, we found that while healthy volunteers showed significant increases in Glu/TCr and Glx/TCr with increasing task difficulty (between the averaged last spectra of the 0-back and the first of the 2-back task conditions), this was not seen in patients with SCZ or BD (17). The gene discussed is SLC30A3; the disease is Behcet disease.