For the multivariate LR model with an enter variable selection method, six characteristics were identified as independent risk factors (Table 2), including primary tumor site (p < 0.001), size (p = 0.042), histology (p = 0.018), grade (p < 0.001), CEA level (p < 0.001), EM (p < 0.001). Here, CEACAM5 is linked to neoplasm.