CD28 and gestational diabetes: In both the GDM and control groups, in comparison with the medium-only culture condition, the anti-CD3/anti-CD28 and the STAg stimulus significantly increased the percentage of CD4+IFN+ T cells (p < 0.0001, Figure 5B), CD4+IL10+ T cells (p < 0.01, Figure 5C) and CD4+IL17+ T cells (p < 0.01, Figure 5D).