TRIM21 and peeling skin syndrome: The Spearman correlation analysis showed that the expression of STAT1 in PB showed a moderate to strong positive correlation with the immune response of pSS patients, including anti-SSA (r = 0.75, p < 0.001), anti-SSB (r = 0.47, p = 0.011), ANA (r = 0.52, p = 0.0031), and IgG (r = 0.58, p < 0.001), and associated with the disease activity based on the ESSDAI index (Figure 7B), in accordance to the results of Barrera et al (31).