To further explore the role of VCAN in tumor environment, gastric cancer single-cell dataset GSE167297 containing deep layer (D1, D2, D3, D4, D5) and superficial layer (S1, S2, S3, S4, S5) of tumor tissues and paired normal tissues (N1, N2, N3, N4) was downloaded and analyzed. The gene discussed is VCAN; the disease is neoplasm.