CD4 and head and neck squamous cell carcinoma: Jiang et al. argue that macrophages, T cells CD8, and T cells CD4 memory are the most commonly infiltrated subtypes of immune cells in HNSCC [60], while Wang et al. found a higher abundance of B cells, CD8+ T cells, neutrophils, and DCs in the low-risk group compared with the high-risk group, which predicts better prognosis [61].