Serpin family E member 1 (SERPINE1), also named plasminogen activator inhibitor type 1 (PAI-1), is a fibrinolysis inhibitor found to be abnormally expressed in gastric cancer [34], colon cancer [35], diffuse lower-grade gliomas [36], and other cancers. The gene discussed is SERPINE1; the disease is malignant colon neoplasm.