The top 10 related signaling pathways are shown in Table 2, including tumor, proteoglycan in cancer, prostate cancer, PI3K-Akt signaling pathway, Ras signaling pathway, thyroid hormone signaling pathway, prolactin signaling pathway, progesterone-mediated oocyte maturation, pancreatic cancer, and FoxO signaling pathways. The gene discussed is TG; the disease is Familial prostate cancer.