ANXA5 and cancer: In our study, flow cytometry analysis revealed that a non-lethal dose of KP372-1 (0.15 μM) or rucaparib (15 μM) alone had no apparent effect on A549 cancer cell growth, while this combination treatment or a lethal dose of KP372-1 (0.4 μM) caused significant apoptosis induction (Annexin-V+/7ADD-) by 48 h (Figure 5A).