When analyzing metastasis rates in different immune landscape categories, we found significantly higher lymph node or overall metastasis rates in type IV (PD-L1-TIL+) cases than type I (PD-L1+TIL+) cases (lymph node metastasis: 69.2% vs. 35.0%, p = 0.03; overall metastasis: 84.6% vs. 50.0%, p = 0.02), suggesting a negative correlation between PD-L1 presence and metastatic status in TIL+ tumors. This evidence concerns the gene CD274 and metastatic malignant neoplasm in the lymph nodes.