The %change of CD40LG remained higher at 24 h post-hypoglycemia in deep-hypo; however, the level did not reach significance (-7.1 ± 2.3 vs. -20.7 ± 12.0%change of soluble CD-40 ligand, study-2 vs. study-1, p = 0.08) (Fig. 2 C). Here, CD40LG is linked to Hypoglycemia.