In control subjects, %change of vWF and plasminogen was greater at 24 h post-hypoglycemia in mild- hypo versus deep-hypo (165.1 ± 71.0 vs. 15.8 ± 8.1%change of vWF at 24 h-posthypo, study-1 vs. study-2, p = 0.001) (Fig. 2D); (16.6 ± 8.9 vs. 2.1 ± 1.5, %change at of plasminogen at 24 h post-hypoglycemia, study-1 vs. study-2, p = 0.013) (Fig. 2E). Here, PLG is linked to Hypoglycemia.