A similarly high %change of vWF was observed in mild-hypo compared to deep-hypo in T2D (112.3 ± 77.1 vs. 17.7 ± 13.0%change of vWF at 24 h post-hypoglycemia, study-1 vs. study-2, p = 0.05) (Fig. 3E). This evidence concerns the gene VWF and type 2 diabetes mellitus.