VWF and Hypoglycemia: Percent change of 4 proteins (PAI-1, CD40LG, Protein S, vWF) differed in control subjects at baseline to hypoglycemia between mild-hypo (study-1) and deep-hypo (study-2); three of these proteins were higher in response to deep transient hypoglycemia (PAI-1, CD40LG, Protein S) and one (vWF) was higher in response to mild prolonged hypoglycemia in control subjects.