In addition, the frequencies of SF3B1, ASXL1, SRSF2, RUNX1, DNMT3A, and EZH2 gene mutations are significantly higher in TET2MT MDS cases compared to TET2WT MDS cases, while the frequencies of SRSF2, ASXL1, RUNX1, CEBPA, DNMT3A, JAK2, FLT3ITD, and SETBP1 gene mutations are significantly higher in TET2MT sAML cases compared to TET2WT sAML cases. The gene discussed is JAK2; the disease is myelodysplastic syndrome.