Furthermore, TYRO3, AXL, MERTK, and their corresponding ligands are involved in independent signaling pathways, with PROS1/AXL signaling pathway-mediated tumour proliferation being dominant in oral squamous cell carcinoma, whereas the other two TAM receptors (MERTK and TYRO3) are nearly undetectable. This evidence concerns the gene AXL and oral cavity squamous cell carcinoma.