After combining the two methods and ROC analysis, eight NSCLC-related biomarkers with accurate predictive properties were identified (the AUCs of all these eight genes were greater than 0.89), including ADAMTS8, ABCA8, TPX2, CEP55, ASPA, FHL1, RAMP3, and PYCR1 genes. This evidence concerns the gene ABCA8 and non-small cell lung carcinoma.