CTSL and Parkinson disease: On the other hand, other cathepsins, such as Cathepsin B (CTSB), is also reported to be released via exosomes30, in consequence, to further confirm the specific pathogenic role of α-Syn oligomers-induced CTSL secretion from microglia in PD pathogenesis, we also detected the CTSB level in exosomes secreted by α-Syn oligomers-activated microglia.