IL1B and hydrops fetalis: The protein markers of pyroptosis in left ventricular tissue of rats were tested by WB, the results revealed that the expression of cleaved caspase‐1, caspase‐1, the ratio of cleaved caspase‐1/caspase‐1, NLRP3, IL‐1β, IL‐18, GSDMD‐N and ASC were significantly up‐regulated in HF rats induced by ISO, and obviously, ECH reversed the changes and down‐regulated the expression of these proteins, as shown in Figure 1G–L.