GSTM1 and Splenomegaly: Bivariate correlation analyses examining trends in RBC lifespan and other variables (see Table 1) across varix severity groups revealed that RBC lifespan was the assessed variable that correlated most robustly with varix severity (r=−0.793, P<0.001) (Fig. 2), followed by splenomegaly (r=0.656, P<0.001), PLT (r=−0.598, P<0.001), Child-Pugh class (r=0.565, P<0.001), RBC (r=−0.340, P=0.013), and Hb (r=−0.308, P=0.025).