For the sake of investigating the part of SCD1 played in RUNX2‐mediated ccRCC cell growth, migration, and invasion, the RUNX2 overexpression cells were transfected with short hairpin (sh) RNAs targeting SCD1 (LV‐RUNX2/shRNA‐SCD1) and the RUNX2 knockdown cells were transfected with viral particles containing the full‐length fragment of SCD1 (shRNA‐RUNX2/LV‐SCD1). This evidence concerns the gene SCD and nonpapillary renal cell carcinoma.