NFKB1 and neoplasm: We found Tan IIA lead to decline in the expression of p-p65-NF-κB, IL-6, and IL-1β of the tumor samples in comparison with the controls (Figure 3, p < 0.01); meanwhile, intestinal dysbacteriosis condition can increase the phosphorylation of p65, IL-6, and IL-1β in Tan IIA-treated mice (Figure 3, p < 0.01).