GZMB and neoplasm: In turn, the NK cells' granzyme B production was significantly increased in the presence of 25 and 50 μM thymoquinone compared with the control tumor cells in the presence of NK cells alone (one-way ANOVA, n = 3, P = 0.0001, and P < 0.0001, respectively, Tukeys), as seen in Figure 2(b).